As the College Football Playoff race heats up in November, Week 10 of the 2022 College Football season features a slew of AP-Top 25 teams in action. While there are only three ranked vs. ranked matchups this week, none are more important than the two SEC conference games this weekend, when Tennessee travels to face Georgia and Alabama visits Tiger Stadium to face LSU.
We have everything you need to make your betting decisions ahead of Week 10 with plenty of questions and games to wager on this weekend. Prior to the release of the College Football Playoff rankings, the AP-25 poll was used to determine the rankings.
Friday
Washington hosts No. 24 Oregon State (-4.5, 60)
10:30 p.m. Husky Stadium, Seattle, Washington, ET
- Washington has failed to cover in all four of its games this season.
- This season, Washington is 4-1 ATS at home.
- Since the start of the 2019 season, Oregon State has gone 10-3 ATS as a road underdog, ranking second in the Pac-12.
- The last three meetings between Oregon State and Washington have all ended in a tie.
Saturday
Northwestern (-38, 62.5) at No. 2 Ohio State
Ryan Field in Evanston, Illinois, airs at noon ET on ABC.
- Northwestern has failed to cover in all four of its home games this season.
- Ohio State is tied with Wisconsin for the longest active over streak in the FBS, having gone over the total in six consecutive games.
- Since the start of the 2017 season, Ohio State has gone 17-4-2 on the road, the highest road over percentage in the FBS (min. 4 road games).
- Ohio State is the biggest favorite against Northwestern since 1983. (-40).
Texas Tech vs. No. 7 TCU (-10, 71)
Amon G. Carter Stadium, Fort Worth, TX, noon ET
- This season, TCU is 6-1-1 ATS, tied for the third-best cover percentage in the FBS.
- This season, TCU’s four home games have all gone over the total.
- This season, Texas Tech is 3-0 ATS after a straight-up loss.
- This season, four of Texas Tech’s five games against AP-ranked opponents went over the total.
North Carolina (-9.5, 59.5) vs. Virginia
Scott Stadium, Charlottesville, Virginia, noon ET on ACC Network
- Virginia is 1-6-1 against the spread this season, tied with Georgia Tech for the lowest over/under percentage in the ACC.
- North Carolina and Virginia have gone over the total in each of their last four meetings.
- Since the start of the 2018 season, Virginia is 4-1 ATS as a home underdog.
- North Carolina has covered four of its last five ACC games.
Tulane (-7.5, 58) vs. Tulsa
Chapman Stadium in Tulsa, Oklahoma, at noon ET on ESPNU.
- Tulane is 7-1 ATS this season, tied for the best cover percentage in the FBS with Tennessee.
- Since the start of the 2018 season, Tulsa is 11-0 ATS against AP-ranked opponents, which is tied for the best such cover percentage in the FBS.
- Tulsa is 9-1-1 ATS as an underdog since the start of the 2020 season, ranking fourth in the FBS in that time period.
- Tulsa has won 13 of the last 17 games it has played against Tulane.
Tennessee at No. 1 Georgia (-9, 65.5)
3:30 p.m. Athens, Georgia (ET), Sanford Stadium
- Tennessee is 7-1 ATS this season, tied for the best cover percentage in the FBS with Tulane.
- Since the 2020 ACC Championship Game, no top-two team has been at least an eight-point underdog (No. 2 Notre Dame was +11 against No. 4 Clemson; Clemson won by 24).
- The nine-point spread is the largest in a 1-vs-2 matchup since the BCS Championship Game in 2013, when No. 1 Florida State was a 9-point favorite over No. 2 Auburn; FSU won by three points.
- Since the 1978 FBS/FCS split, underdogs are 24-12-1 ATS and 20-17 overall, including 4-0 ATS in the last ten seasons (2-2 SU).
- Since 1978, 1-vs-2 underdogs of at least 7 points are 8-2 ATS and 6-4 SU (1-2 ATS and SU last 15 seasons).
No. 8 Oregon (-31.5, 60.5) visits Colorado.
3:30 p.m. Folsom Field, Boulder, Colorado, ET on ESPN
- This season, Colorado is 0-5 ATS against teams with winning records.
- Since the start of last season, Colorado is 3-0 ATS against AP-ranked opponents.
- Oregon has covered the last three games (all as a favorite).
- Oregon is 5-2-1 ATS this season, which ranks second in the Pac-12.
No. 14 Illinois hosts Michigan State (-16, 43.5)
3:30 p.m. Memorial Stadium, Champaign, Illinois, 3 p.m. ET
- Since the start of the 2015 season, Illinois is 7-2-1 ATS as a double-digit favorite.
- This season, Illinois is 4-1 ATS at home and has covered five of its last six games overall.
- Michigan State has won nine of its last twelve games against Illinois.
- This season, Michigan State is 1-4 ATS against teams with winning records.
Penn State (-13.5, 54.5) at Indiana
3:30 p.m. Memorial Stadium, Bloomington, Indiana, on ABC
- Since the start of last season, Indiana is 1-6 ATS against AP-ranked opponents.
- Since the start of last season, Indiana is 3-11 ATS as an underdog, the lowest cover percentage in the Big Ten (min. 2 games).
- Under James Franklin, Penn State is 8-22-1 ATS after a straight-up loss, the lowest such cover percentage in the FBS since the start of the 2014 season (min. 2 games played following a straight-up loss).
- Penn State has gone over the total in all three of its games this season.
Oklahoma State (-3.5, 69) at Kansas
3:30 p.m. Lawrence, Kansas, David Booth Kansas Memorial Stadium, ET
- This season, Kansas is 6-1-1 ATS, tied for the third-best cover percentage in the FBS.
- Oklahoma State has won all four of its games against Kansas.
- Since the start of last season, Oklahoma State is 7-1 ATS on the road. Over that time period, that is the best road cover percentage in the FBS.
- Since the start of last season, Oklahoma State is 11-2-1 ATS in Big-12 play, the best such cover percentage in the Big 12.
Syracuse (22nd) vs. Pittsburgh (-3.5, 50.5)
3:30 p.m. ET on the ACC Network, Acrisure Stadium, Pittsburgh, PA
- This season, Pittsburgh is 1-4 ATS at home, tied for the lowest home cover percentage in the ACC.
- This season, Pittsburgh is 0-3 ATS against teams with winning records.
- The total has been under in the last three meetings between Syracuse and Pittsburgh.
- Syracuse is 6-2 ATS this season, tied for the best ACC cover percentage with Wake Forest.
UCF (-3.5, 61.5) vs. Memphis
3:30 p.m. Liberty Bowl Memorial Stadium in Memphis, Tennessee, at 2:00 p.m. ET on ESPN2.
- Memphis has covered its last six home games as a favorite.
- Memphis is 7-1 against the spread this season, which is tied for the highest over/under percentage in the FBS.
- Since the start of the 2019 season, Memphis is 1-7 ATS against AP-ranked opponents.
- In nine of its last twelve road games, UCF has gone over the total.
No. 23 Liberty vs. Arkansas (-14, 64.5)
4 p.m. Razorback Stadium, Fayetteville, Arkansas, 7:00 p.m. ET on SEC Network
- This season, Arkansas has gone over the total in all four of its home games.
- This season, Arkansas is 7-1 to the over, tied for the highest over percentage in the FBS.
- This season, Liberty has gone over the total in all four of its road games.
- Since the start of the 2020 season, Liberty is 5-1 ATS as a road underdog.
No. 6 Alabama (-13, 58) visits No. 15 LSU.
7 p.m. Tiger Stadium, Baton Rouge, Louisiana, ET on ESPN
- Since the start of the 2019 season, LSU is 5-0 ATS after a bye week.
- Since the start of the 2017 season, LSU is 15-4-1 ATS against AP Top-10 teams.
- As a double-digit favorite, Alabama has covered four of its last five games.
- Alabama has a 15-game winning streak against LSU (12-3 SU, 9-6 ATS).
No. 13 Kansas State (-1.5, 54.5) vs. Texas
7 p.m. Manhattan, Kansas (ET), Bill Snyder Family Stadium
- Since the start of last season, Texas is 1-6 ATS on the road. Over that time period, the Big 12 had the lowest road cover percentage.
- Following a straight-up loss, Texas has covered its last three games.
- This season, Kansas State is 4-1 ATS at home.
- Over the last ten seasons, Kansas State is 16-6 ATS as a home underdog, the best such cover percentage in the Big 12.
No. 4 Michigan (-26.5, 45.5) visits Rutgers.
7:30 p.m. SHI Stadium, Piscataway, New Jersey, ET
- This season, Michigan is 1-6-1 against the spread, the lowest in the Big Ten.
- Since the start of last season, Rutgers is 1-4 ATS as a home underdog.
- The total has been exceeded in seven of the last eight meetings between Michigan and Rutgers.
- Since the start of the 2019 season, Michigan is 20-12 ATS as a favorite, tied with Minnesota for the best such cover percentage in the Big Ten.
Clemson (-3.5, 47.5) vs. Notre Dame
7:30 p.m. Notre Dame Stadium, Notre Dame, Indiana, 3 p.m. ET
- This season, Notre Dame has yet to cover a game at home (0-4 ATS).
- Notre Dame has only been a home underdog seven times since 2014. They are 5-1 ATS in their last six games.
- This season, Notre Dame is 3-0 ATS against teams with winning records.
- Since the start of the 2018 season, Clemson is 15-7 ATS as a road favorite.
No. 12 Arizona vs. Utah (-17.5, 67.5)
7:30 p.m. Salt Lake City, Utah, ET, Rice-Eccles Stadium
- This season, Utah is 4-0 ATS as a double-digit favorite.
- Utah has failed to cover the spread in each of its last three games.
- This season, Arizona is 4-0 ATS after a straight-up loss.
- This season, Arizona has gone over the total in all three of its road games.
Wake Forest (-3.5, 54) vs. No. 21 NC State
8 p.m. Carter-Finley Stadium, Raleigh, North Carolina, ET on ACC Network
- Wake Forest is 6-2 ATS this season, tied for the best ACC cover percentage with Syracuse.
- Wake Forest has covered its last four games after suffering a straight-up loss.
- Since the start of the 2015 season, Wake Forest has gone 16-5 against AP-ranked teams.
- NC State has failed to cover in all five of its games this season.
UCLA (-10.5, 62) at Arizona State
9:30 p.m. Sun Devil Stadium, Tempe, Arizona, 3 p.m. ET
- Arizona State has won seven of its last eight games against AP top-10 opponents, including four outright victories (one against No. 7 UCLA in 2015).
- The 7-1 ATS record against AP top-10 opponents is tied for the best cover percentage in the FBS with Minnesota (min. 5 games).
- UCLA is 4-1 SU and ATS in Pac-12 play this season, with the only loss coming Oct. 22 at No. 10 Oregon as a 7-point underdog.
- Arizona State is 13-4 ATS as a double-digit underdog over the last ten seasons, which ranks second in the FBS (min. 15 games).
- UCLA had covered the spread in four straight games against Arizona State before losing outright as a three-point home favorite last year.
No. 9 USC in California (-12, 58)
10:30 p.m. Los Angeles Memorial Coliseum, Los Angeles, California, ET on ESPN
- In the last five seasons, California is 12-3 ATS as a road underdog, which is tied for the best cover percentage in the FBS with Oklahoma State (min. 10 games).
- Since Pete Carroll’s departure after the 2009 season, USC is 7-11 ATS as a 21-point favorite, tied for the sixth-worst cover percentage in the FBS (min. 15 games).
- In this series, the under has hit in 14 of the last 17 games.
- The over has hit in all three of USC’s games this season against teams with a losing record.